Foundations of Clinical Research Applications to Evidence-Based Practice

1. Frameworks for Generating and Applying Evidence
2. On the Road to Translational Research
3. Defining the Research Question
4. The Role of Theory in Research and Practice
5. Understanding Evidence-Based Practice
6. Searching the Literature
7. Ethical Issues in Clinical Research
8. Principles of Measurement
9. Concepts of Measurement Reliability
10. Concepts of Measurement Validity
11. Designing Surveys and Questionnaires
12. Understanding Health Measurement Scales
13. Choosing a Sample
14. Principles of Clinical Trials
15. Design Validity
16. Experimental Designs
17. Quasi-Experimental Designs
18. Single-Subject Designs
19. Exploratory Research: Observational Designs
20. Descriptive Research
21. Qualitative Research
22. Descriptive Statistics
23. Foundations of Statistical Inference
24. Comparing Two Means: The t-Test
25. Comparing More Than Two Means: Analysis of Variance
26. Multiple Comparison Tests
27. Nonparametric Tests for Group Comparisons
28. Measuring Association for Categorical Variables: Chi-Square
29. Correlation
30. Regression
31. Multivariate Analysis
32. Measurement Revisited: Reliability and Validity Statistics
33. Diagnostic Accuracy
34. Epidemiology: Measuring Risk
35. Writing a Research Proposal
36. Critical Appraisal: Evaluating Research Reports
37. Synthesizing Literature: Systematic Reviews and Meta-Analyses
38. Disseminating Research

Conceptual descriptions of analytic procedures used in EBP as well as tables that demonstrate simple calculations Algorithm for choosing a statistical procedure based on a study’s design Diagrams that help students understand experimental and observational design variations Guidelines for critical appraisal of various types of studies Focus on sensitivity/specificity and likelihood ratios, number needed to treat, and measuring clinically meaningful change Special features that illustrate how research applies to practice, including, “Case-in Point,” “Fun Facts,” “Historical Notes,” and end-of-chapter ‘take-away’ commentaries from the author